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Case studies (e.g

Modulation of pentose phosphate pathway during cell cycle progression in human colon adenocarcinoma cell line HT29

Glutamate and cysteine are synthesized into gamma-glutamylcysteine by gamma-glutamylcysteine synthetase (GCL) and then combined with glycine by GSH synthase to synthesize GSH (48)

This D-retro-inverso configuration preserves the three-dimensional side-chain topology of the original FOXO4 sequence maintaining functional mimicry of the FOXO4 forkhead domains interaction surface with p53 while conferring exceptional proteolytic stability compared to the native L-amino acid sequence