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Promotes smooth, clear skin Encourages strong nails Contributes to full and shiny hair Helps to clear up skin problems Can reduce the visibility of aging and scars Can help to build lean muscle Promotes a healthy metabolism Encourages joint repair and strong bones Aids in appetite control and weight management Promotes gut health &amp

Chronic hyperglycemia-induced ROS overproduction, primarily derived from mitochondrial ETC leakage and NOX activation, leads to eNOS uncoupling due to BH4 oxidation, reducing NO bioavailability and impairing vasodilation (Giacco and Brownlee, 2010)

In addition, omega-3 improves mitochondrial function and reduces inflammation-induced oxidative stress, which overall contributes to the maintenance of lean body tissue (71, 72)

doi: 10.1016/j.redox.2022.102380 16 NagataKKakizakiYYanagidaKAraiTNakanoKHamanoFet al