The role of aldose reductase in polyol pathway: an emerging pharmacological target in diabetic complications and associated morbidities
All clinic staff involved in product dispensing, visit assessments, conduct of the study, monitoring charts and analysis of outcomes remained blinded for the duration of the study
In many malignancies, the remodeled ECM expresses high levels of the elastin protein which may have either positive or negative effects on tumor growth
Red-flag criteria include rapid lesion growth, marked asymmetry, ulceration or spontaneous bleeding, nodularity, color variegation, induration, fixation to underlying tissues, pain, or associated systemic symptoms, all of which warrant prompt referral and histopathological evaluation to exclude malignancy [12,14,34,35,36,37]