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Description

FIGURE 4 5.2 Ferroptosis and DOR Abnormalities in iron metabolism are associated with various degenerative diseases, and granulosa cells, oocytes, and their supporting cells in the ovary are particularly sensitive to OS (Stockwell et al., 2017)

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Nec-1 functions through the specifically targeting of Receptor-Interacting Protein Kinase 1 (RIPK1), inducing disruption in the assembly of the necrosome, consequently impeding the execution of necroptotic cell death