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Ghusn W, De La Rosa A, Sacoto D, Cifuentes L, Campos A, Feris F, et al

More specifically, the FD&C Act requires that bulk drug substances used to compound must: comply with the standards of an applicable United States Pharmacopeia (USP) or National Formulary (NF) monograph, if a monograph exists, and the USP chapter on pharmacy compounding

[0087] 34.8 g of crude Semaglutide was weighed, dissolved in 1500 mL of a mixed solvent of 25% acetonitrile and 75% water, and purified using Waters 2545 RP-HPLC system with a wavelength of 218 nm, a chromatographic column of 50 x 250 mm reverse phase C18 column, a column temperature of 45C, and NaClO4 and acetonitrile as a mobile phase system

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