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Zepbound contains tirzepatide, a dual-acting medication that targets both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors

Each time the tirzepatide dose increases , the body needs to readjust to stronger appetite suppression, more pronounced gastric slowing, and faster weight loss

To minimize them, doctors typically start with a low dose and gradually increase it over time

Retatrutide is a synthetic peptide molecule engineered to mimic and activate three naturally occurring hormone pathways involved in metabolism: GIP receptor activity associated with glucose-dependent insulin signaling and metabolic regulation