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It works through a different mechanism (fat oxidation via beta-3 adrenergic receptors, not appetite suppression), and that mechanism produces gradual, subtle changes

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Recent Mendelian randomization findings further validate this framework: Dorea and Sellimonas appear protective, whereas Phascolarctobacterium and Ruminococcaceae UCG-004 are associated with increased PTSD risk (He et al., 2024)

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