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Secondary outcomes encompass MACEs, including stroke (either ischemic or hemorrhagic), acute myocardial infarction (AMI), cardiac arrest, cardiogenic shock or death, as well as major adverse kidney events (MAKEs), which is defined as a composite of dialysis dependence, an eGFR less than 15 mL/min/1.73 m, or death

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The allure is that glutathione is an antioxidant (something the body naturally has) so it feels safer than the notorious hydroquinone creams or mercury-laced lightening products of the past