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The 28-day rule United States Pharmacopeia (USP) general guidelines indicate multi-dose vials containing preservatives such as benzyl alcohol may be used for up to 28 days after the initial puncture, provided they are stored properly and free from visible contamination

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Compared with controls, adherent SC-islets treated with ZnPTO exhibited a higher proportion of EGFP + GCG + cells, supporting the hypothesis that excessive zinc induces the conversion of SC- cells into SC- cells (Supplementary information, Fig