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A systematic review presented today at the Endocrine Society's annual meeting in Chicago, Illinois, suggests that GLP-1 medications might increase testosterone levels and help to improve the quality of sperm in men with obesity

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Berberine regulates the mRNA levels of glucose-regulated protein 78 (GRP78), CCAAT/enhancer binding protein (C/EBP) -homologous protein (CHOP), procaspase-3/9/12 in Alzheimers disease rats hippocampus, which involve in the endoplasmic reticulum stress pathway (Xuan et al., 2020)

Ozempic is a newer option that increases production of insulin and slows gastric emptying