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he is also a developer of novel biological drugs, including GLP-1 agonists, and holds several US patents in the field

Our data demonstrate that the replenishment of mucosal GSH attenuates the extent of mucosal injury, suggesting the potential therapeutic use of repleting GSH levels early during the development of colitis

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Elevated intracellular cAMP levels activate protein kinase A (PKA), which phosphorylates multiple downstream targets including transcription factors like CREB (cAMP response element-binding protein)