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The frequency of menstrual changes in placebo groups was lower but not zero, confirming that some disruption stems from weight reduction rather than the drug itself

The second is that competitors who cannot match the rebate structure face a compounding disadvantage: the more market share the incumbent gains, the larger the retroactive rebate it earns, the more the PBM is financially motivated to protect that incumbents formulary position

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[DOI] [PMC free article] [PubMed] [Google Scholar] 36.La Sala L., Mrakic-Sposta S., Tagliabue E., Prattichizzo F., Micheloni S., Sangalli E., Specchia C., Uccellatore A.C., Lupini S., Spinetti G., et al