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As expected, those taking semaglutide lost more weight than those in the placebo group

When to Contact Healthcare Providers : Patients should seek medical advice if side effects are severe, persistent beyond two weeks, or interfering with daily activities

The long half-life ensures consistent drug levels regardless of injection time

The C-peptide area under the curve (AUC) 0 30 min /glucose AUC 0 30 min , an index of insulin secretion, increased from 159.5 17.13 pmol mmol 1 to 169.96 19.3 pmol mmol 1 in R, but remained constant (157.89 7.81 pmol mmol 1 to 161.81 8.15 pmol mmol 1 ) in NR ( P group over time = 0.043