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This strategy, explored over the last two decades, has recently been successful using GST-activated nitrogen mustard (TLK286) and GT-activated arsenic-based (GSAO and Darinaparsin) prodrugs confirming the potential of GSH-conjugates as anticancer drugs
The solution should develop a blue tint confirming copper chelation
Therefore, any therapeutic strategy for the abuse of these drugs should target the improvement of the efficacy and tolerability of DA transporters and other molecular targets (Table 1) in clinical disorders
Since they work differently, they can actually complement each other
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