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Studies investigating vitamin B 6 status throughout pregnancy have reported a dramatic decline of plasma pyridoxal phosphate (PLP) concentration with up to 70 % lower values in late pregnancy in comparison with the concentrations postpartum (Reference Bjrke-Monsen, Varsi and Sakkestad49) or in age matched non-pregnant controls (Reference Trumbo and Wang60)

It has also been reported that obese women with high GPx activity have an altered cardiometabolic profile, evidenced by insulin resistance predominantly affecting the liver, altered carbohydrate and lipid metabolisms, and a larger wall thickness of blood vessels than those with lower GPx activity