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However, the endothelial damage observed in ME/CFS patients does not appear to correlate with the usual markers of endothelial dysfunction seen in cardiovascular disease such as increased levels of symmetric dimethylarginine (SDMA), asymmetric dimethylarginine (ADMA), and high-sensitivity C-reactive protein (hs-CRP), and reduced levels of arginine and homoarginine (311)

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Rarely, erectile dysfunction and loss of libido have been reported when taking beta-sitosterol, which is found in certain Prostate Supplements as well as some Cholesterol-Lowering Supplements

Systemic versus topical approach Unlike KPV and GHK-Cu, which are primarily studied as topical applications for skin conditions, TB-500 works systemically