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Following this, all mice received a single bolus injection intraperitoneally, consisting of one of the following tracers: [ 15 N, 13 C 5 ]valine (100 mg kg 1 ), [ 15 N, 13 C 4 ]threonine (100 mg kg 1 ), or [ 13 C 3 ]propionate (500 mg kg 1 )

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Would discontinuing metformin (Metformin) for Janumet (Sitagliptin/Metformin) and Mounjaro (Tirzepatide) be indicated in a patient with unimproved hyperglycemia, currently at an HbA1c of 10.2% on metformin 500mg four times a day (qid)?