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Topical exfoliant preparations, known as keratolytics, are generally recommended because physical exfoliation (such as with a loofa) can cause further skin irritation if used too vigorously

Status: FDA-approved (HSDD in premenopausal women) SC injection as-needed Available via prescription Caveat: Transient nausea, flushing, and blood pressure changes are common

When muscle is lost during weight management, it can result in: Decreased metabolic rate Reduced physical strength and endurance Difficulty maintaining weight loss long-term Diminished quality of life and functional capacity For those using medical weight management approaches, these concerns become even more pressing, as the accelerated weight loss can sometimes lead to greater muscle breakdown without proper nutritional support

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