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In contrast, UC affects only the colon and rectum continuously, with inflammation restricted to the mucosa ( Scientific evidence that increased levels of reactive oxygen species (ROS) but decreased levels of antioxidants contribute to disease pathogenesis establishes a link between ROS and IBD ( In vitro and in vivo studies have demonstrated that the activation of the transcription factor hypoxia-inducible factor (HIF) functions as a warning signal in several murine disease models

Reprod Fertil Dev 31:282293 Kim JH, Pan JH, Lee ES, Kim YJ (2015) LC enhances exercise endurance