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The HPA axis also integrates into this network: gut microbes can affect cortisol dynamics by influencing the hosts metabolism of tryptophan into metabolites like kynurenine that impact HPA feedback loops [46, 47]

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133 In addition to dopaminergic agents, intravenous lidocaine has been shown to transiently suppress tinnitus perception, although its effect is short-lived

28 In addition, homocysteine is known to cause endothelial (protective lining) damage, a recognized contributor to the progressive loss of kidney function