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This narrative review aims to synthesize current evidence on the physiological and therapeutic relevance of GLP-1 signaling in sepsis, highlight mechanistic insights from preclinical studies, and assess the translational potential of GLP-1RAs in modulating systemic inflammation, metabolic dysregulation, and organ dysfunction in septic states

Thus, Ozempic represents a shift towards more integrated, holistic management of diabetes, addressing multiple aspects of the disease beyond just glucose control

Phospholipase iPLA2 averts ferroptosis by eliminating a redox lipid death signal

These weight loss medications work by mimicking the action of the glucagon-like peptide-1 hormone to regulate blood sugar levels and promote weight loss