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35-37 The pivotal CHAMPION trial indicated that use of PA pressure monitoring in patients with HF results in reduced rates of HF hospitalizations, and the subgroup analysis of HFpEF resulted in similar outcomes

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Nonetheless, the subpar target selectivity and chemical stability of these inhibitors restrict their use

Contact your healthcare provider if you notice cardiovascular symptoms such as persistent rapid heart rate (tachycardia), palpitations, chest discomfort, or dizziness, particularly if these symptoms are new or worsening