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A history of cardiac symptoms, a family history concerning for cardiac dysrhythmias, or abnormal physical examination or electrocardiography findings should prompt a more in-depth evaluation for heart disease

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Future experiments are needed to identify the relationship between the binding property of hypnotics and the degree of side effects, including a decrease in sleep quality

The study also: Compared tirzepatide with phentermine rather than placebo Identified pain through diagnosis and prescription records Did not directly measure each patients pain severity Could not fully separate the effects of weight loss from medication-specific effects Could not prove that tirzepatide caused the reduction in pain encounters The findings support further research, but they are not enough to classify tirzepatide as a joint-pain or arthritis medication