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These trials highlight the favorable effects of each new class of T2D therapy on CV parameters, seemingly resulting in a large paradigm shift in diabetes care and impact on decision-making in the selection of antidiabetic agents to improve prognosis [5, 6]

Treatment also improved motor activity and increased BDNF, which promotes neuroplasticity and protection [108]

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But as millions of patients ramp up to the maximum clinical dosages, a startling reality has emerged: the biological cost of rapid, pharmaceutical weight loss is incredibly high