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Together, the complexity of ENDS devices and liquids, suggest that the toxic effects of ENDS aerosols may not be solely due to the toxicants (or carbonyls) emitted from the device but may also be due to the chemical forms of nicotine (free-base nicotine vs nicotine salt) interacting with the other components of the e-liquid

High UA has been associated with endothelial dysfunction in postmenopausal women, suggesting that high UA could be an independent risk factor for cardiovascular disease, including AF and CHD, particularly among postmenopausal women (Maruhashi et al., 2013

Juul, the e-cig maker started at Stanford, watches its US market share get vaporized

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