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Eric Topol (44:17): And I guess just in finishing the discovery of this class of drugs and what it's led to, tells us something about that, there's so much more to learn that is, this has taken on perhaps the greatest obstacle in medicine, which was could you safely treat obesity and have a marked effect

If you want to widen the comparison, move back into the broader diet-support route and check the actual product composition carefully

Contact your prescriber or seek urgent care if you develop widespread hives, significant swelling, breathing difficulties, or symptoms suggestive of anaphylaxis

This creates an evidence gap, meaning prescribing decisions must be based on careful risk-benefit analysis rather than robust trial data in this specific population