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As mentioned above, deciphering the significance of systemic insulin resistance and adequate glycaemic control in neurodegenerative diseases remains an evolving field

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2.3.5 Epigallocatechin gallate (EGCG) EGCG, the principal catechin of green tea ( Camellia sinensis ), attenuates PsO-like inflammation through inhibition of STAT3 phosphorylation, NF-B signaling, and Th17 differentiation [52] In keratinocyte and IMQ mouse models, EGCG reduces IL-17/IL-22 production, oxidative stress, and keratinocyte hyperproliferation

This makes them feel very unwell, and extremely worried that they will sustain irreversible neurological damage