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Incorrect dosing may result in inadequate therapeutic effect or increased adverse events including nausea, vomiting, and diarrhea

Temperatures directly against this wall can drop below freezing, even if the overall fridge temperature is set correctly

For instance, laboratory tests from Novo Nordisk, the manufacturer of Wegovy and Ozempic, have shown that these semaglutide formulations can safely stay unrefrigerated for up to 28 days for Wegovy and 56 days for Ozempic without losing efficacy or risking contamination

[55] Inflammation and oxidative stress [edit] In metabolic conditions like obesity and diabetes, chronic inflammation and oxidative stress drive cellular damage and insulin resistance