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How GLP-1 drug costs and coverage are shaping the market The Optum Rx Strategic Insights area recently completed a deep dive into how GLP-1 drugs are affecting the prescription drug market

Its decline during menopause accelerates the sarcopenic trajectory that estrogen withdrawal initiates, and its restoration, where clinically appropriate, may help counteract the muscle loss that rapid weight loss compounds

A 2024 KFF survey revealed that about 1 in 8 American adults have tried a GLP-1 agonist, which works by mimicking a natural hormone in the body that regulates insulin and blood sugar levels while promoting feelings of fullness, helping the average patient shed 10% to 15% of their body weight

Retatrutides higher discontinuation rate due to adverse events, combined with the dysesthesia signal, places a greater tolerability burden on participants compared to tirzepatide [3]