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Public health explanations of addiction emphasize that nicotine changes how the brain responds over time, which is why cravings can feel urgent and why quitting can be rough

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We provide a short synopsis of Prohibition crime and smuggling in "Appendix B: Prohibition in Michigan and the Avenue de Booze." In this appendix we motivate and discuss the empirical models and results used to produce the casual and commercial smuggling estimates presented in the main text under "A New Estimate of Interstate Cigarette Smuggling Rates" (see Page 12)

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