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Efficacy and safety of aldafermin, an engineered FGF19 analog, in a randomized, double-blind, placebo-controlled trial of patients with nonalcoholic steatohepatitis
And regulatory approvals already reflect this shift: Wegovy is approved to lower cardiovascular risk, Ozempic slows kidney disease progression, and semaglutide is cleared for metabolic dysfunctionassociated steatohepatitis (MASH) with fibrosis
Otherwise very safe water-soluble
Though it is not universal, a fair percentage of those on a ketogenic diet become L-carnitine deficient (absolute or relative), and demonstrate better control of epileptic events, as well as respond better to medication when supplemented with L-carnitine
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