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This oxidative imbalance might stabilize and activate NRF2 by disrupting its KEAP1-mediated degradation (Kre et al., 2023)

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Adv Biosci Biotechnol 3:9971019 Isaac R, Boura-halfon S, Gurevitch D, Shainskaya A, Levkovitz Y, Zick Y (2013) Selective serotonin reuptake inhibitors (SSRIs) inhibit insulin secretion and action in pancreatic -cells