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showed that ARID1A-deficient cancer cells expressed low levels of the key cystine transporter SLC7A11 and thus exhibited low basal levels of GSH, which made these cancer cells specifically vulnerable to inhibition of the GSH metabolic pathway 25

Some patients report a brief second wave of mild headaches when their dose increases, but this recurrence is typically shorter and less intense than the initial episode

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Aging (Albany NY) (2021) 13(3):461733