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25 In 2005, exenatide was approved by the U.S
The STEP 5 trial demonstrated that continued treatment for 104 weeks maintained weight loss, while the STEP 1 extension study showed that discontinuing semaglutide at 68 weeks led to two-thirds of the weight lost being regained within a year
Some individuals may need a review of their dose or a talk with a doctor about other treatment options, depending on their goals and how well they tolerate the medicine
Researchers conducted a population-based cohort study to determine if GLP-1RA use results in higher melanoma and nonmelanoma skin cancer risk than sulfonylureas in T2DM patients [73]
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