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Biomolecules 5:318342 Baudouin-Cornu P, Lagniel G, Kumar C, Huang ME, Labarre J (2012) Glutathione degradation is a key determinant of glutathione homeostasis

ROS are a necessary defense system to combat microbial respiratory infections (Lambeth, 2004), but oxidative stress and the excessive production of ROS by numerous cells including monocytes and macrophages, neutrophils, as well as pulmonary endothelial and epithelial cells play a major role in the development of ARDS and its complications during COVID-19 infections (Meftahi et al., 2021)

10.1016/S0140-6736(17)32804-0 46

Trans-ISRIB treatment Cell assay For immunostaining of adherent SC-islets, cells were treated with 7 M trans-ISRIB, with or without 3 M ZnPTO added to the cell culture medium, for 24 h in an incubator (37 C, 5% CO 2 )