Enter a vast array of sunless tanning products, from self-tanning lotions to serums to nasal spray
Both compounds have been the subject of extensive peer-reviewed scientific literature and are among the most widely referenced peptides in contemporary research settings
Pramlintide was engineered from native human amylin with three proline substitutions at positions 25, 28, and 29 to prevent the amyloid fibril formation that makes native amylin unsuitable for pharmaceutical use
Exenatide GLP-RA , 1995 2005 .60 Liraglutide 2010 2 ,62 lixisenatide 2013 2 , 2 016 7 .63 (Albiglutide) 2014 3 , 2014 4 .64 (Dulaglutide) 2014 9 T2DM ,65 (Semaglutide) 2017 9 .66 (Beinaglutide) GLP-RA , 2016 9 T2DM .67 PEG-(PEG-loxenatide) GLP-RA , 2019 5 .66 ( 1 2) Table 1 Comparison of GLP-1RAs used in type 2 diabetes mellitus DateBrand nameGLP-1RAHalf-lifeDose (SC)Molecular formulaClinial trial focus Table 2 Comparative overview of efficacy and adverse effects of mainstream GLP-1RA medications Current GLP-1RAs GLP-1RAs are synthetic protein preparations that have partial or complete amino acid sequence homology with GLP-1 found in the body, are not easily degraded, have longer half-lives and have stronger biological activity
