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Central nervous system regulation of eating: Insights from human brain imaging

17 A trial of a cow's milkfree diet may also be considered because constipation can be caused by intolerance to cow's milk, especially in young children with anal fissures

483,484 It is worth mentioning that many investigations have reported aberrant melatonin secretion in autistic patients, particularly decreased melatonin and metabolite secretion at night, and altered circadian rhythms of melatonin