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Per-Batch HPLC + Disulfide Bond Verification Because the lipolytic conformation depends on an intact Cys7-Cys14 disulfide bond, every released lot is checked both by HPLC for peptide purity and by non-reducing LC-MS or Ellman's reagent analysis for disulfide bond integrity

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In asymptomatic patients with risk factors (see Table 1: Patient Risk Factors Associated with B 12 Deficiency below) consider supplementation in lieu of testing

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