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These two genes were duplicated during the second whole-genome duplication event (2R) to create four new somatostatin genes: SS1, SS2, SS3 , and one gene that was lost during the evolution of vertebrates

Sources: PMID 18271889, 36986081, 38320260, 38365549, 39186190, 40005053 Saffron is having a moment its kind of amazing because its the most expensive spice in the world yet all of these benefits keep popping up around what it can do as a Supplement

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Szab D, Tod P, Glncsr F et al (2022) Maternal P2X7 receptor inhibition prevents autism-like phenotype in male mouse offspring through the NLRP3-IL-1 pathway