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[1] [3] There is no established pharmacological mechanism by which semaglutide would directly cause gastrointestinal bleeding, based on current evidence
Moreover, tirzepatide outperformed semaglutide when it came to weight loss, with tirzepatide doses of 15 mg, 10 mg, and 5 mg delivering notable reductions in body weight (-10.96 Kg, -8.75 Kg, and -6.16 Kg, respectively) compared to semaglutide (-5.24 Kg, -4.44 Kg, and -2.72 Kg for semaglutide at 2.0, 1.0, and 0.5 mg, respectively)
People with known sleep disorders : the metabolic activation effect can worsen insomnia if dosed late in the day