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Psychological boost: Unlike purely physical aids, PT-141 may reduce anxiety around intimacy, contributing to better performance and satisfaction

While effective for symptom control, NSAIDs carry risks of gastrointestinal ulceration and bleeding, cardiovascular events, renal impairment, and impaired bone and tendon healing

doi: 10.2337/db15-0443

Mendelian randomization evidence indicates that elevated KYN levels have a causal relationship with increased risk of depression, with each standard deviation increase in KYN corresponding to ~ 1.4-fold higher odds of developing depression [50]