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In PD, pairing novel markers, such as seed amplification assays and extracellular vesicle cargo profiling, with specialized imaging modalities (e.g., neuromelanin-sensitive MRI, susceptibility-weighted imaging for iron deposition) has yielded superior diagnostic accuracy and staging resolution [603, 604]

Aunque la relevancia de estos hallazgos en humanos es incierta, se recomienda precaucin, sobre todo en pacientes con antecedentes personales o familiares de carcinoma medular de tiroides

Titration typically involves four to five dose steps over 16 to 20 weeks, with each step building on your previous tolerance

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