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Firstly, by dampening inflammatory responses integral to the pathophysiology of depression and anxiety, omega-3 PUFAs and their metabolites can inhibit leukocyte chemotaxis, reduce the expression of adhesion molecules, decrease the production of pro-inflammatory mediators, and encourage a shift in microglia polarization towards a reparative, non-inflammatory state (75, 76)

Understanding these intricate interactions is essential for developing effective therapies

Because of the potential toxicity and safety concerns related to herbal products, there is a need to establish a pharmacovigilance system of herbal medicines that is integrated within communities and health facilities, so that data regarding their composition, preparation, indications, and adverse events can be gathered (Ozioma and Chinwe, 2019)

For more information on why, and to understand the risks associated with using supplements, please visit Supplement Connect