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Local hypoxia and upregulation of hypoxia-activated genes, like hypoxia-inducible factor-1 (HIF-1) and vascular endothelial growth factor (VEGF), have been described in adipose tissue from mice and humans in obesity [13,14]

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World Health Organization, International Program on Chemical Safety Riley RT, Wang E, Merrill AH (1994) Liquid chromatographic determination of sphinganine and sphingosine: use of the free sphinganine-to-sphingosine ratio as a biomarker for consumption of fumonisins

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