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They framed the gutbrain axis as a dynamic bidirectional signaling network whose dysregulation underlies a broad spectrum of neurogastrointestinal diseases, positioning EVs as key mediators of intercellular communication and promising non-invasive biomarkers Derived from both host and microbial cells, EVs carry bioactive cargo, including proteins, lipids, nucleic acids, and metabolites, that reflects the physiological or pathological state of their origin and can traverse biological barriers such as the bloodbrain barrier
Wendy Spearman, Amalia Gastaldelli, Mrio Guimares Pe Clinical Gastroenterology and Hepatology .2026;[Epub] CrossRef Overcoming the barriers in the screening, diagnosis, and follow-up of patients with metabolic dysfunctionassociated steatotic liver disease (MASLD) and metabolic dysfunctionassociated steatohepatitis (MASH) Roberto Vettor, Maria Letizia Petroni, Idit Dotan, Gadi Lalazar, Martin Haluzk, C