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Our mechanistic investigations revealed that intracellular GSSG elevation sensitizes hepatocytes to TNF killing by inducing IKK--SSG formation, leading to suppressed NF-B activation

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Based on our results, SGLT2is were associated with a lower rate of vision-threatening DR, diabetic nephropathy, and diabetic neuropathy, and GLP1-RAs were associated with the reduction of ischemic stroke and major adverse limb events

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