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Patients experiencing adverse reactions are encouraged to contact their healthcare provider promptly

Whether the heptapeptide fragment fully recapitulates the parent proteins effects in vivo is unresolved

The Kraus 2014 Nature Paper: Why Adipose Research Specifically The 2014 Nature paper by Kraus and colleagues (titled "Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity") established the adipose-NNMT connection that anchors all subsequent NNMT-inhibition research in fat biology