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Role of mitochondrial reverse electron transport in ROS signaling: potential roles in health and disease

However, the absence of cysteine leads to insufficient GPX4 synthesis, increased expression of wild-type p53, and increased cell sensitivity to ferroptosis (Ji et al., 2021)

To minimize these undesired effects, it is imperative to elucidate the mechanisms underlying hyperglucagonemia before translating GCGR antagonism into clinical practice

Therefore, it's reasonable to hypothesize that the co-supplementation of GSH with SeNPs would have a synergistic protective effect on the cryopreservation efficiency of bull spermatozoa